Abstract Background Tests for association between a haplotype and disease are commonly performed using a likelihood ratio test for heterogeneity between case and control haplotype frequencies. Using data from a study of association between heroin dependence and the DRD2 gene. we obtained estimated haplotype frequencies and the associated likelihood ratio statistic using two different ... https://partnersspigenes.shop/product-category/collections/
Minor differences in haplotype frequency estimates can produce very large differences in heterogeneity test statistics
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