Dispensing and dilution processes may profoundly influence estimates of biological activity of compounds. Published data show Ephrin type-B receptor 4 IC50 values obtained via tip-based serial dilution and dispensing versus acoustic dispensing with direct dilution differ by orders of magnitude with no correlation or ranking of datasets. We generated computational 3D pharmacophores bas... https://www.roneverhart.com/Funko-Vinyl-Gold-Premium-Figure-NFL-Browns-Baker-Mayfield-Chase/